The Skin Wrinkle Improvement Effect of Mixed Extracts of Bletilla striata Reichenbach fil., Ampelopsis japonica, Atractylodes japonica, etc.

Purpose: The purpose of this study is to evaluate the skin wrinkle improvement effect a mixture Bletilla striata Reichenbach fil., Ampelopsis japonica, Angelica dahurica, Atractylodes Ligusticum sinense Oliv, officinale, and gigas (BAA).Methods: In study, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity evaluation, SOD (superoxide dismutase)-like activity, xanthine oxidase inhibitory anti-wrinkle test, hyaluronic acid production confirmation, cytotoxicity evaluation were performed cosmetic functionality fermented mixed extract.Results: As result ABTS analysis, BAA-4 was highest at 500 μg/mL (63.7%). DPPH 61.4%. SOD-like it found that increased 33.0±3.7% concentration μg/mL. for analysis result, same as showed 1.3±2.8% collagenase elastase (46.1±3.6% 51.9±3.9%, respectively). content, be 257.4 ng/mL, cell viability more than 95% allconcentrations, confirming all extracts (BAA-1 4) had no cytotoxicity. Conclusion: These research results suggest extract has an excellent collagen promoting can applied safe natural wrinkleimproving material does not cause irritation.